Target organ toxicity

1-Describe the toxicity of a skin toxicant of your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity?Phototoxicitytetracyclines,2-Describe the toxicity of a renal toxicant of your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity?(Cadmium – proximal tubular dysfunction and injury)3-Describe the toxicity of a cardiotoxicantof your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity?(Antipsychotics: may alter function through autonomic effects – anticholinergic effects, negative inotropic effects and QT prolongation.)4-Describe the toxicity of a blood toxicant of your choice under organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity.?Toxic Effects on Clot Formation – warfarin5-Describe the toxicity of a GI toxicant of your choice under the headings of organ susceptibility, mechanisms of toxicity & target structures and assessment of toxicity.?Chemotherapeu1cs-Chemotherapy induced diarrhea (CID): is a common and severe side effect of colorectal cancer chemotherapy – 50 % of CRC patients taking 5FU (also for other therapies)please follow this point.You should write about chemicals that induces toxicity to specific organ. there are five organs which are (skin- Kidney- blood- heart and Gastrointestinal tract).you have to consider these points:1- which this organ susceptibility to toxicity2- mechanisms of toxicity of chemicals3target structures and the chemical/ biological factor that influent toxicity in the organ4- how we can assessment of toxicity1000 max word for each organ, so total 5000 wordsI have already chosen the chemicals for each organs:1-skin-2-Kidney-3-blood-4-heart-5-Gastrointestinal tract-