Literature Critique
I will upload article to critique
1. Select a pharmaceutical random controlled trial (RTC) research article, published within the past 5 years.
2. Answer the following questions:
? What is the purpose of the study?
? Name the study design and analytic methods.
? List the study variables?
? How was this sample size determined?
? What were the age, gender, race, specific diagnostic criteria and socioeconomic status of the participants in this trial? Who was excluded?
? Did the sample size [change/stay the same/disappear]. What was your final sample size? How the people who dropped out compare on [measure of severity of the disorder]? How did the people who dropped out compare on [side effects]?
? How much more effective is this drug than [older, better-known drugs]?
? What was the clinical measure used for the outcome?
? Was the clinical outcome that was measured relevant to clients?
? How long has this drug been on the market?
? What is the data on the development of side effects; how long do they take to develop?
? What is the data on side effects that might be expected to diminish over time?
? Were measurements stopped prior to the point at which serious side effects develop?
3. Summarize the strengths and weaknesses of the research. This is your opinion as to the efficacy, safety & utility of this pharmaceutical agent for the intended population
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